Patterico's Pontifications

4/5/2020

President Trump Advises Americans To Try Hydroxychloroquine, If They’d Like

Filed under: General — Dana @ 1:05 pm



[guest post by Dana]

During his Coronavirus Task Force briefing yesterday, President Trump didn’t just promote hydroxychloroquine, he encouraged people to take it to treat coronavirus. This after Dr. Hahn (FDA Commissioner) cautioned about its use:

DR. HAHN:

I’m going to speak about hydroxychloroquine and the efforts around that…Last week as the president said, we issued an emergency use authorization to allow the donated hydroxychloroquine to come into the country and enter the general circulation. We are prioritizing this drug to come in for clinical trials, also to general use for physicians because, as you know, physicians, based upon their interaction with the patients, their assessment of the risks and benefits, can write a prescription for hydroxychloroquine if they think it’s appropriate for that patient. Being a physician, we do this all the time, and that assessment needs to be done between a patient and a doctor. And then the third portion is we wanted to make sure that these drugs were in the supply chain so that people who have them or need them for the other indications, lupus, rheumatoid arthritis, had them available. So that was the purpose of the emergency use authorization.

PRESIDENT TRUMP (later in the briefing):

One of the reasons that I keep talking about hydroxychloroquine is that the question that nobody ever asks, and the question that I most hate the answer to is what happens if you do have a ventilator? What are your chances? I just hope that hydroxychloroquine wins. Coupled with perhaps the Z pack, as we call it, dependent totally on your doctors, and the doctors there.

Because you know the answer to that question. If you do have the ventilator, you know the answer to that question. I hate giving the answer, so I don’t want to get them there. I don’t want to get them there. There’s a possibility, a possibility, and I say it. What do you have to lose? I’ll say it again. What do you have to lose? Take it. I really think they should take it, but it’s their choice, and it’s their doctor’s choice or the doctors in the hospital. But hydroxychloroquine. Try it, if you’d like.

But I’ve seen some results now. It’s early, I guess. It’s early, and they should look at the lupus thing. I don’t know what it says, but there’s a rumor out there that, because it takes care of lupus very effectively as I understand it. It’s a drug that’s used for lupus.

So there’s a study out there that says people that have lupus haven’t been catching this virus. No. Maybe it’s true. Maybe it’s not. Why don’t you investigate that?

And there’s also other studies with the malaria that the malaria countries have very little people that take this drug for malaria, which is very effective for malaria, that those countries have very little of this virus. I don’t know. You’re going to check it out. But I think people should … If it were me, in fact, I might do it anyway. I may take it. Okay. I may take it, and I’ll have to ask my doctors about that, but I may take it.

And there was more from Dr. Trump:

During the briefing, as Dr. Fauci and other advisers looked on, the president talked about the potential of other medicines, too. He mentioned azithromycin, often referred to as a Z-Pak, which has been given to some patients along with hydroxychloroquine.

“The other thing, if you have a heart condition, I understand, probably you stay away from the Z-Pak. But that’s an antibiotic. It can clean out the lung. The lungs are a point of attack for this horrible virus.”

The President of the United States is putting any number of Americans at potential risk, not only by touting the drug, but by casually advising them to try it, like it was a Tic-Tac. It is apparent that the President has become increasingly reckless about what he says. More so than he was in March, when he said of the drug: “It’s been around for a long time, so we know that if things don’t go as planned it’s not going to kill anybody.” And it doesn’t lessen the potential damage by throwing in the caveat, “it’s their doctor’s choice or the doctors in the hospital.” I’ve said it a million times: Trump holds the most powerful position in the world, and his words carry that much more weight because of it. He plays fast and loose with the facts, contradicts the medical experts standing next to him, and has the temerity to disagree with these same experts after they clean up his verbal messes. This is reckless behavior, and because of his directive, people might fall ill, or even die. And if they do, because they stupidly followed his advice, then Trump would bear some level of moral responsibility. These are dangerous times, and when the chief executive cavalierly tells Americans to take a drug and has no idea how it might affect them, he potentially endangers them. And while I don’t believe that the vast majority of Americans would take medical advice from Trump, there is a loyal base of true believers who hang on his every word. So much so, in fact, that they put him into office.

Meanwhile, the President might want to read this:

[A] study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. The study comes on the heels of two others – one in France and one in China – that reported some benefits in the combination of hydroxychloroquine and azithromycin for COVID-19 patients who didn’t have severe symptoms of the virus.

I am a medicinal chemist who has specialized in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven. I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.

There are already other clinical studies that showed it is not effective against COVID-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving people false hope. The latter has led to widespread shortages of hydroxychloroquine for patients who need it to treat malaria, lupus and rheumatoid arthritis, the indications for which it was originally approved…Thus, despite the recent approval of this drug for use against COVID-19, questions remain as to the efficacy of this treatment. As Molina and colleagues note: “Ongoing randomized clinical trials with hydroxychloroquine should provide a definitive answer regarding the alleged efficacy of this combination and will assess its safety.”

You can watch the press conference from yesterday here.

–Dana

Sunday Music: Bach’s St. Matthew Passion, BWV 244: Opening Chorus

Filed under: Bach Cantatas,General,Music — Patterico @ 12:01 am



It is Palm Sunday. Today’s Bach piece is music you might expect to hear on Palm Sunday, the day that we hear the Passion story according to St. Matthew. Namely, the opening chorus from Bach’s St. Matthew Passion: “Kommt, ihr Töchter, helft mir klagen” (Come, daughters, help me lament):

Today’s Gospel reading is the Passion story according to St. Matthew: Matthew 26:14-27:66.

Judas Agrees to Betray Jesus

Then one of the Twelve—the one called Judas Iscariot—went to the chief priests and asked, “What are you willing to give me if I deliver him over to you?” So they counted out for him thirty pieces of silver. From then on Judas watched for an opportunity to hand him over.

The Last Supper

On the first day of the Festival of Unleavened Bread, the disciples came to Jesus and asked, “Where do you want us to make preparations for you to eat the Passover?”

He replied, “Go into the city to a certain man and tell him, ‘The Teacher says: My appointed time is near. I am going to celebrate the Passover with my disciples at your house.’” So the disciples did as Jesus had directed them and prepared the Passover.

When evening came, Jesus was reclining at the table with the Twelve. And while they were eating, he said, “Truly I tell you, one of you will betray me.”

They were very sad and began to say to him one after the other, “Surely you don’t mean me, Lord?”

Jesus replied, “The one who has dipped his hand into the bowl with me will betray me. The Son of Man will go just as it is written about him. But woe to that man who betrays the Son of Man! It would be better for him if he had not been born.”

Then Judas, the one who would betray him, said, “Surely you don’t mean me, Rabbi?”

Jesus answered, “You have said so.”

While they were eating, Jesus took bread, and when he had given thanks, he broke it and gave it to his disciples, saying, “Take and eat; this is my body.”

Then he took a cup, and when he had given thanks, he gave it to them, saying, “Drink from it, all of you. 28 This is my blood of the covenant, which is poured out for many for the forgiveness of sins. I tell you, I will not drink from this fruit of the vine from now on until that day when I drink it new with you in my Father’s kingdom.”

When they had sung a hymn, they went out to the Mount of Olives.

Jesus Predicts Peter’s Denial

Then Jesus told them, “This very night you will all fall away on account of me, for it is written:

“‘I will strike the shepherd,
and the sheep of the flock will be scattered.’

But after I have risen, I will go ahead of you into Galilee.”

Peter replied, “Even if all fall away on account of you, I never will.”

“Truly I tell you,” Jesus answered, “this very night, before the rooster crows, you will disown me three times.”

But Peter declared, “Even if I have to die with you, I will never disown you.” And all the other disciples said the same.

Gethsemane

Then Jesus went with his disciples to a place called Gethsemane, and he said to them, “Sit here while I go over there and pray.” He took Peter and the two sons of Zebedee along with him, and he began to be sorrowful and troubled. Then he said to them, “My soul is overwhelmed with sorrow to the point of death. Stay here and keep watch with me.”

3oing a little farther, he fell with his face to the ground and prayed, “My Father, if it is possible, may this cup be taken from me. Yet not as I will, but as you will.”

Then he returned to his disciples and found them sleeping. “Couldn’t you men keep watch with me for one hour?” he asked Peter. “Watch and pray so that you will not fall into temptation. The spirit is willing, but the flesh is weak.”

He went away a second time and prayed, “My Father, if it is not possible for this cup to be taken away unless I drink it, may your will be done.”

When he came back, he again found them sleeping, because their eyes were heavy. So he left them and went away once more and prayed the third time, saying the same thing.

Then he returned to the disciples and said to them, “Are you still sleeping and resting? Look, the hour has come, and the Son of Man is delivered into the hands of sinners. Rise! Let us go! Here comes my betrayer!”

Jesus Arrested

While he was still speaking, Judas, one of the Twelve, arrived. With him was a large crowd armed with swords and clubs, sent from the chief priests and the elders of the people. Now the betrayer had arranged a signal with them: “The one I kiss is the man; arrest him.” Going at once to Jesus, Judas said, “Greetings, Rabbi!” and kissed him.

Jesus replied, “Do what you came for, friend.”

Then the men stepped forward, seized Jesus and arrested him. With that, one of Jesus’ companions reached for his sword, drew it out and struck the servant of the high priest, cutting off his ear.

“Put your sword back in its place,” Jesus said to him, “for all who draw the sword will die by the sword. Do you think I cannot call on my Father, and he will at once put at my disposal more than twelve legions of angels? But how then would the Scriptures be fulfilled that say it must happen in this way?”

In that hour Jesus said to the crowd, “Am I leading a rebellion, that you have come out with swords and clubs to capture me? Every day I sat in the temple courts teaching, and you did not arrest me. But this has all taken place that the writings of the prophets might be fulfilled.” Then all the disciples deserted him and fled.

Jesus Before the Sanhedrin

Those who had arrested Jesus took him to Caiaphas the high priest, where the teachers of the law and the elders had assembled. But Peter followed him at a distance, right up to the courtyard of the high priest. He entered and sat down with the guards to see the outcome.

The chief priests and the whole Sanhedrin were looking for false evidence against Jesus so that they could put him to death. But they did not find any, though many false witnesses came forward.

Finally two came forward and declared, “This fellow said, ‘I am able to destroy the temple of God and rebuild it in three days.’”

Then the high priest stood up and said to Jesus, “Are you not going to answer? What is this testimony that these men are bringing against you?” But Jesus remained silent.

The high priest said to him, “I charge you under oath by the living God: Tell us if you are the Messiah, the Son of God.”

“You have said so,” Jesus replied. “But I say to all of you: From now on you will see the Son of Man sitting at the right hand of the Mighty One and coming on the clouds of heaven.”

Then the high priest tore his clothes and said, “He has spoken blasphemy! Why do we need any more witnesses? Look, now you have heard the blasphemy. What do you think?”

“He is worthy of death,” they answered.

Then they spit in his face and struck him with their fists. Others slapped him and said, “Prophesy to us, Messiah. Who hit you?”

Peter Disowns Jesus

Now Peter was sitting out in the courtyard, and a servant girl came to him. “You also were with Jesus of Galilee,” she said.

But he denied it before them all. “I don’t know what you’re talking about,” he said.

Then he went out to the gateway, where another servant girl saw him and said to the people there, “This fellow was with Jesus of Nazareth.”

He denied it again, with an oath: “I don’t know the man!”

After a little while, those standing there went up to Peter and said, “Surely you are one of them; your accent gives you away.”

Then he began to call down curses, and he swore to them, “I don’t know the man!”

Immediately a rooster crowed. Then Peter remembered the word Jesus had spoken: “Before the rooster crows, you will disown me three times.” And he went outside and wept bitterly.

Judas Hangs Himself

Early in the morning, all the chief priests and the elders of the people made their plans how to have Jesus executed. So they bound him, led him away and handed him over to Pilate the governor.

When Judas, who had betrayed him, saw that Jesus was condemned, he was seized with remorse and returned the thirty pieces of silver to the chief priests and the elders. “I have sinned,” he said, “for I have betrayed innocent blood.”

“What is that to us?” they replied. “That’s your responsibility.”

So Judas threw the money into the temple and left. Then he went away and hanged himself.

The chief priests picked up the coins and said, “It is against the law to put this into the treasury, since it is blood money.” So they decided to use the money to buy the potter’s field as a burial place for foreigners. That is why it has been called the Field of Blood to this day. Then what was spoken by Jeremiah the prophet was fulfilled: “They took the thirty pieces of silver, the price set on him by the people of Israel, and they used them to buy the potter’s field, as the Lord commanded me.”

Jesus Before Pilate

Meanwhile Jesus stood before the governor, and the governor asked him, “Are you the king of the Jews?”

“You have said so,” Jesus replied.

When he was accused by the chief priests and the elders, he gave no answer. Then Pilate asked him, “Don’t you hear the testimony they are bringing against you?” But Jesus made no reply, not even to a single charge—to the great amazement of the governor.

Now it was the governor’s custom at the festival to release a prisoner chosen by the crowd. 16 At that time they had a well-known prisoner whose name was Jesus Barabbas. So when the crowd had gathered, Pilate asked them, “Which one do you want me to release to you: Jesus Barabbas, or Jesus who is called the Messiah?” For he knew it was out of self-interest that they had handed Jesus over to him.

While Pilate was sitting on the judge’s seat, his wife sent him this message: “Don’t have anything to do with that innocent man, for I have suffered a great deal today in a dream because of him.”

But the chief priests and the elders persuaded the crowd to ask for Barabbas and to have Jesus executed.

“Which of the two do you want me to release to you?” asked the governor.

“Barabbas,” they answered.

“What shall I do, then, with Jesus who is called the Messiah?” Pilate asked.

They all answered, “Crucify him!”

“Why? What crime has he committed?” asked Pilate.

But they shouted all the louder, “Crucify him!”

When Pilate saw that he was getting nowhere, but that instead an uproar was starting, he took water and washed his hands in front of the crowd. “I am innocent of this man’s blood,” he said. “It is your responsibility!”

All the people answered, “His blood is on us and on our children!”

Then he released Barabbas to them. But he had Jesus flogged, and handed him over to be crucified.

The Soldiers Mock Jesus

Then the governor’s soldiers took Jesus into the Praetorium and gathered the whole company of soldiers around him. They stripped him and put a scarlet robe on him, and then twisted together a crown of thorns and set it on his head. They put a staff in his right hand. Then they knelt in front of him and mocked him. “Hail, king of the Jews!” they said. They spit on him, and took the staff and struck him on the head again and again. After they had mocked him, they took off the robe and put his own clothes on him. Then they led him away to crucify him.

The Crucifixion of Jesus

As they were going out, they met a man from Cyrene, named Simon, and they forced him to carry the cross. They came to a place called Golgotha (which means “the place of the skull”). There they offered Jesus wine to drink, mixed with gall; but after tasting it, he refused to drink it. When they had crucified him, they divided up his clothes by casting lots. And sitting down, they kept watch over him there. Above his head they placed the written charge against him: this is jesus, the king of the jews.

Two rebels were crucified with him, one on his right and one on his left. Those who passed by hurled insults at him, shaking their heads and saying, “You who are going to destroy the temple and build it in three days, save yourself! Come down from the cross, if you are the Son of God!” In the same way the chief priests, the teachers of the law and the elders mocked him. “He saved others,” they said, “but he can’t save himself! He’s the king of Israel! Let him come down now from the cross, and we will believe in him. He trusts in God. Let God rescue him now if he wants him, for he said, ‘I am the Son of God.’” In the same way the rebels who were crucified with him also heaped insults on him.

The Death of Jesus

From noon until three in the afternoon darkness came over all the land. 46 About three in the afternoon Jesus cried out in a loud voice, “Eli, Eli, lema sabachthani?” (which means “My God, my God, why have you forsaken me?”).

When some of those standing there heard this, they said, “He’s calling Elijah.”

Immediately one of them ran and got a sponge. He filled it with wine vinegar, put it on a staff, and offered it to Jesus to drink. The rest said, “Now leave him alone. Let’s see if Elijah comes to save him.”

And when Jesus had cried out again in a loud voice, he gave up his spirit.

At that moment the curtain of the temple was torn in two from top to bottom. The earth shook, the rocks split and the tombs broke open. The bodies of many holy people who had died were raised to life. They came out of the tombs after Jesus’ resurrection and went into the holy city and appeared to many people.

When the centurion and those with him who were guarding Jesus saw the earthquake and all that had happened, they were terrified, and exclaimed, “Surely he was the Son of God!”

Many women were there, watching from a distance. They had followed Jesus from Galilee to care for his needs. Among them were Mary Magdalene, Mary the mother of James and Joseph, and the mother of Zebedee’s sons.

The Burial of Jesus

As evening approached, there came a rich man from Arimathea, named Joseph, who had himself become a disciple of Jesus. Going to Pilate, he asked for Jesus’ body, and Pilate ordered that it be given to him. Joseph took the body, wrapped it in a clean linen cloth, and placed it in his own new tomb that he had cut out of the rock. He rolled a big stone in front of the entrance to the tomb and went away. Mary Magdalene and the other Mary were sitting there opposite the tomb.

The Guard at the Tomb

The next day, the one after Preparation Day, the chief priests and the Pharisees went to Pilate. “Sir,” they said, “we remember that while he was still alive that deceiver said, ‘After three days I will rise again.’ So give the order for the tomb to be made secure until the third day. Otherwise, his disciples may come and steal the body and tell the people that he has been raised from the dead. This last deception will be worse than the first.”

“Take a guard,” Pilate answered. “Go, make the tomb as secure as you know how.” So they went and made the tomb secure by putting a seal on the stone and posting the guard.

The text of today’s piece is available here. It contains these words:

Come, daughters, help me lament,
behold! – Whom? – the Bridegroom!
Behold him! – how? – As a Lamb.
Behold! – what? – behold the patience,
look! – where? – at our guilt.
See him, out of love and graciousness
bear the wood for the Cross Himself.
O innocent Lamb of God,
slaughtered on the trunk of the Cross,
patient at all times,
however you were scorned.
you have borne all sins,
otherwise we would have to despair.
Have mercy on us, o Jesus.

The St. Matthew Passion is very important to me. I explained in a post in December 2017:

As regular readers know, I have begun to post a Bach cantata every Sunday, with eight entries so far and counting. I feel funny saying this, but Bach’s music has even motivated me to go to church again. I was raised in the Episcopal church, but Bach’s example spurred me to look for a Lutheran church, and I found one nearby that has a very welcoming congregation where I feel very comfortable. Commenter DRJ noted something that I had never heard before: that Bach’s cantatas have been called “the fifth Gospel.” Indeed:

Yuko Maruyama, a Japanese organist working in Minneapolis, was once a devout Buddhist. Now, thanks to the music of J. S. Bach, she is a Christian. “Bach introduced me to God, Jesus, and Christianity,” she told Metro Lutheran, a Twin Cities monthly. “When I play a fugue, I can feel Bach talking to God.” Masashi Masuda, a Jesuit priest, came to faith in almost the same way: “Listening to Bach’s Goldberg Variations first aroused my interest in Christianity.” Today Masuda teaches theology at Tokyo’s Sophia University.

But why would the most abstract works of an 18th-century German composer guide Asian people to Christ? Charles Ford, a mathematics professor in St. Louis, suggests that this is because Bach’s music reflects the perfect beauty of created order to which the Japanese mind is receptive. “Bach has had the same effect on me, a Western scientist,” explained Ford. Henry Gerike, organist and choirmaster at Concordia Seminary in St. Louis, agrees: “The fugue is the best way God has given us to enjoy his creation. … But of course Bach’s most significant message to us is the Gospel.” Gerike echoes Swedish archbishop Nathan Söderblom (1866–1931), who famously called Bach’s cantatas “the fifth Gospel.”

I can’t easily explain it in words, and it makes me feel a little sheepish to talk about it, but my experience has been much the same. After listening to Bach, I just felt drawn to the church, and I couldn’t really articulate precisely why when people asked. But it makes sense to me inside, and that’s all that matters.

The music that drew me back to the church and to God will always have a very special place in my heart. This is that music. I am very pleased to be able to share it today with all of you, on this special day.

And it is an even more special day, because today is also my mother’s birthday.

Happy listening! Soli Deo gloria.

P.S. Speaking of the Last Supper, a friend of mine on Facebook posted this image of the Last Supper in the time of the coronavirus:

Screen Shot 2020-04-04 at 11.08.18 PM


Powered by WordPress.

Page loaded in: 0.0639 secs.